To prevent creating multiple data locations, which can cause difficulties when maintaining the UI and data, it is Tealium best practice to roll the data from each client-side profile into the server-side main profile. There are a number of benefits, including a single data location, a single server-side profile to configuration new attributes, connectors, etc., and a single Visitor Profile across markets and/or regions.
From here, Data Sources and Event Feeds can be used to filter the data accordingly.
It would make sense to not roll data into the server-side main profile if a client would like to keep all data between markets and/or regions completely separate from one another.
To ensure full functionality, contact your Customer Success Manager about submitting a Data Source Sync for each client-side profile. A Data Source Sync automatically creates Event Attributes for any Data Layer items added in the client-side profile that have been published to Prod. This helps cut down on manual configuration within the server-side profile.