We're a .NET stack as well (but C#) and pleased to say we have absolutely no issues with TiQ (including working with the datalayer). I would suggest trying everything without deviation - if you can keep to the common standard then all the better (and as @steve_lake mentioned, you likely won't have any issues). With so much great reference material here, it really helps being able to directly apply examples without having to do a bunch of special adjustments to make it work with a non-standard setup. Your JS should run just fine in any APSX file.
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